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Chemicals

MRTX-1257

Consultar

DESCRIPCIÓN

Supplier:Biorbyt
Reference:orb1308008
Name:MRTX-1257
Category:Chemicals
Subcategory:Small Molecules
Unit:10 mg
price :Consultar
note :2206736-04-9
purity :99,07%
specificactivity :MRTX-1257 is a selective, irreversible, and covalent inhibitor of KRAS G12C. It has an IC50 of 900 pM for KRAS dependent ERK phosphorylation in H358 cells. MRTX1257 demonstrated 31% bioavailability in the mouse, with free fraction exposures well above the
Molecular weight :565,71


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